When the surgeon removes the tumor from the patient, determining whether they have taken out all the cancer cells or whether more tissue should be extracted is a problem they face. Usually, the edge of the tumor is evaluated after the surgery is completed, and if it looks like some cancer is left behind, additional surgery may be necessary. Therefore, developing a method for real-time detection of cancerous tissue is very useful for both surgeons and patients.
Cancer Test Pen: The MasSpec Pen, as its name suggests, is a small pen device that can determine if a tissue has become cancerous in as little as 10 seconds. It works by delivering a drop of water to the surface of the tissue. The droplet draws molecules from the tissue and then analyzes it with a mass spectrometer. The mass spectrometer can quickly measure the mass of the chemical and then the system reports whether the tissue is cancerous or normal. With this information, the doctor can decide whether to continue to remove the tissue or whether all the cancer cells have been removed.
The researchers tested MasSpec Pen on 253 samples of body tissue and found that 96% was accurate. They are now using pens that can analyze smaller parts of the organization. The team acknowledges that the mass spectrometer is quite large and expensive, and makes the MasSpec Pen as useful as possible, so a smaller and cheaper version will be needed.
Others have developed different methods for real-time analysis of cancerous tissues, including surgery that can distinguish cancer from normal brain tissue, fluorescence-assisted imaging systems, and recent microscopes.
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